It would be nice to have a nice high-level wrapper class for key Clojure integration functions. In IronPython for example, there is a IronPython.Hosting.Python class. For ClojureCLR, I created the attached clojure.lang.Hosting.Clojure class which provides three simple functions Require, GetVar, and AddNamespaceLoadMapping (for integrating .clj files into .NET assemblies as embedded resources). This class or one like it is a simple suggestion to make integration with existing code as painless as possible.
Clojure.GetVar("clojure.main", "main").invoke(); // Starts an embedded Clojure REPL
This is much simpler than:
Symbol CLOJURE_MAIN = Symbol.intern("clojure.main");
Var REQUIRE = RT.var("clojure.core", "require");